TNFRSF3

Lymphotoxin beta receptor (LT beta R), also known as TNF C receptor and TNF R2rp, was originally identified as a transcribed sequence with homology to the TNF receptor superfamily. The cytoplasmic region of LT beta R shares little sequence similarity with other TNF receptor family members, suggesting that different signaling mechanisms may be utilized. LT beta R is expressed in a variety of tissues including visceral and lymphoid tissues. The human and mouse LT beta R share 76% amino acid sequence identity.

Product Specifications

Synonyms

LTBR; CD18; TNFCR; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III

NCBI Gene ID

4055

UniProt

P36941

Accession Number

NP_002333.1

Accession Number mRNA

NM_002342

Chromosomal Location

8q24

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human TNFRSF3 EC domain

Clone

(#3T24)

Applications

WB, FC

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.