TIE-2

Tie-2 is an endothelial-specific receptor tyrosine kinase and a receptor for angiopoietins. Tie-2 is predominantly expressed in the endothelium and it is likely involved in the regulation of vascular maturation and stability.

Product Specifications

Synonyms

Angiopoietin-1 receptor; Endothelial tyrosine kinase; HYK; STK1; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK; CD202b; Tek; Hyk; Tie2; AA517024

NCBI Gene ID

21687

UniProt

Q02858

Accession Number

NP_038718.2

Accession Number mRNA

NM_013690.2

Chromosomal Location

4 C5; 4 43.34 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Mouse Tie2 extracellular domain

Clone

(#MAB080)

Applications

WB, IHC, FC

Purification Method

Protein A/G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS (sterile)

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.