T-cell Immunoglobulin Mucin-2 (TIM-2)
TIM-2 is a type I membrane protein and is a member of the TIM protein family. TIM-2 has an immunoglobulin variable region-like domain followed by a mucin-like domain in its extracellular region.This protein family is characterized by their conserved immunoglobulin and mucin domains, as well as by their expression on activated T cells. TIM-2 is a receptor for Semaphorin 4A, which is expressed on dendritic cells and B cells. Semaphorin 4A has been shown to enhance T cell activation.
Product Specifications
Synonyms
Timd2; G9D3; Tim2; TIM-2; C78111; AA816106; AU019358; AU019662
NCBI Gene ID
171284
UniProt
Q8R183
Accession Number
NP_599010.4
Accession Number mRNA
NM_134249.5
Chromosomal Location
11 B1.1; 11
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein of TIM-2
Clone
(#5B23)
Applications
WB, IHC (P)
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
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