TARC (CCL17)
TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant human TARC is an 8.0 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CCL17; TARC; ABCD-2; SCYA17; A-152E5.3
NCBI Gene ID
6361
UniProt
Q92583
Accession Number
NP_002978.1
Accession Number mRNA
NM_002987
Chromosomal Location
16q13
Reactivity
Human
Cross Reactivity
Mouse, Human, Bacteria
Sequence
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human T cells using a concentration range of 1.0-10.0 ng/ml.
Length
71
Form
Lyophilized
Molecular Weight
8 kDa
Host or Source
E. coli
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