What is the catalog number for Synuclein alpha?

The catalog number for Synuclein alpha is 500-094.

What sizes are available for Synuclein alpha?

Synuclein alpha is available in the following size(s): 100 µg.

Is Synuclein alpha in stock?

Synuclein alpha is currently made to order / not held in immediate stock. Contact us for lead time.

Synuclein alpha

Alpha-Synuclein is a member of the Synuclein family. It is expressed principally in brain but also expressed in low concentrations in all tissues except liver. Alpha synuclein interacts with UCHL1, Phospholipase D and histones. In addition, alpha synuclein is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that alpha synuclein is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in its action will lead to Dementia Lewy Body (DLB) .Human Alpha-Synuclein, is also known as Non-A Beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1. Recombinant Human alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed, and purified as periplasmic protein by ion-exchange chromatography.

Product Specifications

Synonyms

Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor (NACP

NCBI Gene ID

6622

UniProt

P37840

Accession Number

NP_000336.1

Accession Number mRNA

NM_000345.4

Reactivity

Human

Sequence

MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA

Assay Protocol

Always centrifuge tubes before opening. Dissolve the lyophilized protein in ddH2O. Mix gently and do not mix by vortex. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Aliquot the reconstituted solution to minimize freeze-thaw cycles.