Sclerostin
SOST, also known as sclerostin, is a member of the Cerberus/DAN family of BMP antagonists, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is expressed by osteoclasts in developing bones of mouse embryos, including both intramembranously forming skull bones and endochondrally forming long bones.
Product Specifications
Synonyms
Sost; 5430411E23Rik
NCBI Gene ID
74499
UniProt
Q99P68
Accession Number
NP_077769.3
Accession Number mRNA
NM_024449.5
Chromosomal Location
11 D; 11
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein of Sclerostin
Clone
(#4D77)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2
Curated Selection
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