What is the catalog number for Resistin antagonist?

The catalog number for Resistin antagonist is 500-093S.

What sizes are available for Resistin antagonist?

Resistin antagonist is available in the following size(s): 2 µg.

Is Resistin antagonist in stock?

Resistin antagonist is currently made to order / not held in immediate stock. Contact us for lead time.

Resistin antagonist

Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins (monomeric peptide contains 11 cysteine residues) referred to as the RELM family, and is also described as ADSF (Adipose Tissue-Specific Secretory Factor) or FIZZ3 (Found in Inflammatory Zone 3) . Human resistin antagonist is a monomeric C7A mutant that does not form covalent dimers. It is expressed and purified by chromatographic techniques.

Product Specifications

Synonyms

Adipose tissue-specific secretory factor (ADSF), C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3

NCBI Gene ID

56729

UniProt

Q9HD89

Accession Number

NP_065148

Accession Number mRNA

NM_020415

Reactivity

Human

Cross Reactivity

Mouse, Human

Sequence

ASSKTLCSMEE AINERIQEVA GSLIFRAISS IGLECQSVTS RGDLATCPRG FAVTGCTCGS ACGSWDVRAE TTCHCQCAGM DWTGARCCRV QP

Assay Protocol

It is recommended to reconstitute the lyophilized resistin in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other buffered aqueous solutions containing carrier proteins.

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

>98.0% as determined by RP-HPLC, SDS-PAGE Silver Stained and Gel filtration.

Bioactivity

The biological activity was evidenced by resistin antagonist activity to inhibit resistin-induced Akt phosphorylation in two cell lines. It also reduced the weight (mainly the visceral fat) and normalized GTT and ITT inHFD-fed mice.