Prox-1
Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lymphatic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Produced from sera of rabbits immunized with the recombinant highly conserved C-terminal part of the homeobox transcription factor Prox-1.
Product Specifications
Synonyms
PROX1; W117m
NCBI Gene ID
5629
UniProt
Q92786
Accession Number
NP_002754.2
Accession Number mRNA
NM_002763.3
Chromosomal Location
1q32.2-q32.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Prox-1 (RT #300-052)
Clone
Rabbit IgG
Applications
WB, IF
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: Use 1-5 µg/ml
Form
Lyophilized
Buffer
0.5X PBS, pH 7.2
Reconstitution
Water
Storage Conditions
Host or Source
Rabbit
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