Prolactin, antagonist (del 1-9) G129R
Prolactin, also known as mammotrophin, luterotropic hormone, and lutetropin, is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human prolactin antagonist del 1-9 G129R mutant has a molecular weight of approx. 22 kDa and contains 190 amino acid residues with an additional N-terminal Alanin.
Product Specifications
Synonyms
Mammotropin, Luterotropic hormone, Lutetropin, PRL
NCBI Gene ID
5617
UniProt
P01236
Accession Number
NP_000939.1
Accession Number mRNA
NM_000948
Chromosomal Location
6p22.2-p21.3
Reactivity
Human
Cross Reactivity
Human
Sequence
Assay Protocol
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 97% by SDS-PAGE & Gel Filtration
Bioactivity
Length
191
Form
Lyophilized
Reconstitution
NaHCO3
Molecular Weight
22 kDa
Host or Source
E. coli
N Terminal Sequence
ARSQVT
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