What is the catalog number for Presenilin-1?

The catalog number for Presenilin-1 is 101-M608.

What sizes are available for Presenilin-1?

Presenilin-1 is available in the following size(s): 100 µg.

Is Presenilin-1 in stock?

Presenilin-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Presenilin-1

Presenilin1 (PS1) is a 467 amino acid multipass lysosomal membrane protein that is a component of the gamma secretase complex. It is cleaved by endoproteolysis at or near amino acid 298 to generate N- and C- terminal fragments. Some mutations in PS 1 are associated with the risk of early onset familial Alzheimer's disease.

Product Specifications

Synonyms

PSEN1; AD3; FAD; PS1; PS-1; S182

NCBI Gene ID

5663

UniProt

P49768

Accession Number

NP_015557.2

Accession Number mRNA

NM_007318.2

Chromosomal Location

14q24.3

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human Presenilin-1

Clone

(#7G6)

Applications

WB, IHC (P)

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.