Pleiotrophin
Human Pleiotrophin (PTN) also called HARP (Heparin affin-regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN and Midkine are structural homologs, and are highly conserved among species. PTN plays an important role in development processes and promotion of neurite extension. Recombinant Pleiotrophin is a 15.4 kDa protein consisting of 136 amino acid residues.
Product Specifications
Synonyms
PTN; HARP; HBNF; HBGF8; NEGF1
NCBI Gene ID
5764
UniProt
P21246
Accession Number
NP_002816.1
Accession Number mRNA
NM_002825
Chromosomal Location
7q33
Reactivity
Human
Cross Reactivity
Mouse, Rat, Human, Chicken, Hamster, Bacteria
Sequence
GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
Assay Protocol
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Data not available.
Length
136
Form
Lyophilized
Reconstitution
Water
Molecular Weight
15.4 kDa
Storage Conditions
Host or Source
E. coli
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