Osteopontin

Osteopontin (OPN), previously referred to as transformation-associated secreted phosphoprotein, bone sialoprotein I, and minopotin, is a secreted, highly acidic, calcium-binding, RGD-containing, phosphorylated glycoprotein originally isolated from bone matrix. Subsequently, OPN has been found in kidney, placenta, blood vessels, and various tumor tissues. Human, mouse, rat, porcine, and bovine OPN share approximately 40% amino acid sequence identity.

Product Specifications

Synonyms

SPP1; OPN; BNSP; BSPI; ETA-1

NCBI Gene ID

6696

UniProt

P10451

Accession Number

NP_001035147

Accession Number mRNA

NM_001040058

Chromosomal Location

4q22.1

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human Osteopontin

Clone

(#1Z3)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.