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Orexin B

Orexin B is a hypothalamic neuropeptide that regulates feeding behavior. This peptide significantly augments food intake in a dose-dependent manner when a bolus was administered intracerebroventricularly. After a 48 hour fast, hypothalamic prepro-orexin mRNA level is up-regulated 2.4. The discovery of Orexins and their receptors may provide a novel molecular basis for understanding the role of the lateral hypothalamic areas in the regulation of energy homeostasis.

Product Specifications

Synonyms

Orexin B

NCBI Gene ID

3060

UniProt

O43612

Accession Number

NP_001515.1

Accession Number mRNA

NM_001524.1

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human Orexin-B peptide (aa71-96, O43621)

Clone

(#5G21)

Applications

IHC (F)

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

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