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NT-3 Recombinant Protein

NT3 a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

Product Specifications

CAS Number

9000-83-3

Synonyms

Ntf3; Nt3; Ntf-3; AI316846; AI835689

NCBI Gene ID

18205

UniProt

P20181

Accession Number

NP_032768.1

Accession Number mRNA

NM_008742.3

Gene Location

6 F3; 6 61.0 cM

Host

E. coli

Origin Species

Mouse

Species Reactivity

Chicken,Cow,Dog,Frog,Hamster,Mouse,Pig,Rat,Human,Monkey

Sequence

MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT

Detection Range

The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.

Endotoxin

< 0.1 ng/µg of protein (<1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Length

120

Form

Lyophilized

Molecular Weight

13.6 kDa

Shipping Conditions

Room Temperature

Frequently Asked Questions

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