NKp80

NKp80, also known as killer cell lectin-like receptor subfamily F, member 1 (KLRF1), is a type II transmembrane protein with a C-type lectin domain in its extracellular region. NKp80 is expressed at the cell surface of virtually all NK cells as a dimer of approximately 80 kDa. It has been shown to function as a co-receptor with natural cytotoxicity receptors (NCR) to induce activation of NK cell-mediated cytolysis.

Product Specifications

Synonyms

KLRF1; NKp80; CLEC5C

NCBI Gene ID

51348

UniProt

Q9NZS2

Accession Number

NP_057607.1

Accession Number mRNA

NM_016523.1

Chromosomal Location

12p13.31

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human NKp80

Clone

(#7D32)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.