What is the catalog number for Nesfatin?

The catalog number for Nesfatin is 100-142S.

What sizes are available for Nesfatin?

Nesfatin is available in the following size(s): 20 µg.

Is Nesfatin in stock?

Nesfatin is currently made to order / not held in immediate stock. Contact us for lead time.

Nesfatin

Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2) . Originally identified as a hypothalamic neuropeptide, Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic isletsβ-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Recombinant human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues.

Product Specifications

Synonyms

Nesfatin, Nucleobindin 2 protein

NCBI Gene ID

4925

UniProt

P80303

Accession Number

NP_005004

Accession Number mRNA

NM_005013.2

Reactivity

Human

Cross Reactivity

Human

Sequence

VPIDIDKTKV QNIHPVESAK IEPPDTGLYY DEYLKQVIDV LETDKHFREK LQKADIEEIK SGRLSKELDL VSHHVRTKLD EL

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analysis

Bioactivity

Determined by an in vivo assay using healthy wild type male mice (C57BL/6J) . Mice were treated via intraperitoneal injection once at a dose of 4μg Nesfatin-1/gm of body weight. Significant effects on body weight and food consumption were observed relative to saline-treated controls.