NAP-2 (CXCL7)
NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP) . NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7-8 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the ELR motif common to CXC chemokines that bind to CXCR1 and CXCR2.
Product Specifications
Synonyms
CXCL7, NAP1L4; NAP2; NAP2L; hNAP2; NAP1L4b
NCBI Gene ID
5473
UniProt
P02775
Accession Number
NP_002695.1
Accession Number mRNA
NM_002704.3
Chromosomal Location
5 E1; 5
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human NAP-2
Applications
ELISA
Purification Method
Ammonium sulfate co-precipitation
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Mouse
Isotype
IgG1, kappa
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