NAP-2 (CXCL7)

NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP) . NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7-8 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the ELR motif common to CXC chemokines that bind to CXCR1 and CXCR2.

Product Specifications

Synonyms

CXCL7, NAP1L4; NAP2; NAP2L; hNAP2; NAP1L4b

NCBI Gene ID

5473

UniProt

P02775

Accession Number

NP_002695.1

Accession Number mRNA

NM_002704.3

Chromosomal Location

5 E1; 5

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant Human NAP-2

Applications

ELISA

Purification Method

Ammonium sulfate co-precipitation

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Form

Lyophilized from PBS

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.