MIP-4 (CCL18)
MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4’s primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
Macrophage Inflammatory Protein-4, CCL18, PARC, DC-CK1, AMAC-1
NCBI Gene ID
6362
UniProt
P55774
Accession Number
NP_002979
Accession Number mRNA
NM_002988
Chromosomal Location
17q11.2
Reactivity
Human
Cross Reactivity
Human, Mouse, Bacteria
Sequence
QVGTNKELC CLVYTSWQIP QKFLVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Length
68
Form
Lyophilized
Reconstitution
Water
Molecular Weight
7.8 kDa
Storage Conditions
Host or Source
E. coli
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