MIP-3 alpha
MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20
NCBI Gene ID
6364
UniProt
P78556
Accession Number
NP_004582.1
Accession Number mRNA
NM_004591
Chromosomal Location
2q33-q37
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant mouse MIP-3 alpha
Applications
ELISA, WB
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Mouse
Isotype
IgG1, kappa
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