MIP-3 alpha

MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Product Specifications

Synonyms

CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20

NCBI Gene ID

6364

UniProt

P78556

Accession Number

NP_004582.1

Accession Number mRNA

NM_004591

Chromosomal Location

2q33-q37

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant mouse MIP-3 alpha

Applications

ELISA, WB

Purification Method

Protein A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Form

Lyophilized from PBS

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.