MIP-1 gamma (CCL9/10)
MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
Product Specifications
Synonyms
Ccl9; CCF18; MRP-2; Scya9; Scya10
NCBI Gene ID
20308
UniProt
P51670
Accession Number
NP_035468.1
Accession Number mRNA
NM_011338.2
Chromosomal Location
11 C; 11 47.4 cM
Reactivity
Mouse
Cross Reactivity
Human
Sequence
QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.
Length
101
Form
Lyophilized
Molecular Weight
11.6 kDa
Host or Source
E. coli
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