MCP-1 (MCAF, CCL2)
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Product Specifications
Synonyms
CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
NCBI Gene ID
6347
UniProt
P13500
Accession Number
NP_002973
Accession Number mRNA
NM_002982
Chromosomal Location
17q11.2-q12
Reactivity
Human
Cross Reactivity
Chicken, Hamster, Monkey, Mouse, Rat, Human, Leech
Sequence
QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Length
76
Form
Lyophilized
Molecular Weight
8.6 kDa
Host or Source
E. coli
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Tex15 Mouse shRNA Lentiviral Particle (Locus ID 104271)
