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Ly-6G (Gr-1)

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI) -linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Gr-1+ cells have recently been implicated in the development of antitumor responses.

Product Specifications

Synonyms

Ly6g; Gr1; Gr-1; Ly-6G

NCBI Gene ID

546644

UniProt

P35461

Accession Number

CAA50269.1

Accession Number mRNA

XM_001475753.2

Chromosomal Location

15 D3; 15

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Cell lysates of mouse neutrophils

Clone

(#6D17)

Applications

FC, IHC (P)

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG2

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