Limitin

Limitin is a secreted interferon (IFN) -like glycoprotein. It has antiviral activity and selectively inhibits B-lineage lymphoid-cell development both in vivo and in vitro, while having little effect on myelopoiesis or erythropoiesis. Limitin binds to the IFN-alpha/beta receptors and induces IFN regulatory factor-1. Mouse limitin displays 32%, 26% and 30% amino acid sequence identity with mouse IFN-alpha, mouse IFN-beta, and human IFN-omega, respectively.

Product Specifications

Synonyms

Ifnz; BGIF; Lmtn; 6030405N23Rik; ENSMUSG00000073810

NCBI Gene ID

319146

UniProt

Q9R1T0

Accession Number

BAA83749

Accession Number mRNA

AB024521.1

Chromosomal Location

4 C4; 4

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Recombinant mouse Limitin

Clone

(#7D19)

Applications

WB, IHC (P)

Purification Method

Protein A/G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.