Leptin
Leptin is a product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin are obese and diabetic, and have reduced activity, metabolism, and body temperature. Rat leptin shares approximately 96% and 82% sequence identity with the mouse and human protein, respectively. The expression of leptin mRNA is restricted to adipose tissue.
Product Specifications
Synonyms
LEP; OB; OBS
NCBI Gene ID
3952
UniProt
P41159
Accession Number
NP_000221.1
Accession Number mRNA
NM_000230
Chromosomal Location
7q31.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human Leptin
Applications
ELISA
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Mouse
Isotype
IgG1, kappa
Curated Selection
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