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Leptin

Leptin is a product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin are obese and diabetic, and have reduced activity, metabolism, and body temperature. Rat leptin shares approximately 96% and 82% sequence identity with the mouse and human protein, respectively. The expression of leptin mRNA is restricted to adipose tissue.

Product Specifications

Synonyms

LEP; OB; OBS

NCBI Gene ID

3952

UniProt

P41159

Accession Number

NP_000221.1

Accession Number mRNA

NM_000230

Chromosomal Location

7q31.1

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant Human Leptin

Applications

ELISA

Purification Method

Protein A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Form

Lyophilized from PBS

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

Host or Source

Mouse

Isotype

IgG1, kappa

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