Leptin antagonist (mutant L39A/D40A/F41A/I42A) Recombinant Protein
Recombinant ovine leptin, one polypeptide chain containing 146 amino and additional Ala at N-terminus acids and having a molecular mass of ~ 16 kDa, ovine leptin was mutated, resulting in L39A/D40A/F41A/I42A mutant was purified by proprietary chromatographic techniques. Preparation of leptin antagonists was published - Niv-Spector et al, Biochem. J 291;221-230 (2005).
Product Specifications
CAS Number
9000-83-3
Synonyms
Lep; ob; obese
NCBI Gene ID
443534
Accession Number
XP_027824581.2
Accession Number mRNA
XM_027968780.2
Host
E. coli
Origin Species
Ovine
Species Reactivity
Ovine
Sequence
AVPIRKVQDDTKTLIKTIVTRINDISHTQSVSSKQRVTGAAAAPGLHPLLSLSKMDQTLAIYQQILASLPSRNVIQISNDLENLRDLLHLLAASKSCPLPQVRALESLESLGVVLEASLYSTEVVALSRLQGSLQDMLRQLDLSPG
Detection Range
Endotoxin
< 0.1 ng/µg of protein (<1EU/µg)
Purity
> 98.0% as determined by Gel filtration and SDS-PAGE gel.
Length
146
Form
Lyophilized
Reconstitution
Molecular Weight
16.0 kDa
Shipping Conditions
Room Temperature
N Terminal Sequence
AVPIR
Frequently Asked Questions
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