LD78-beta/CCL3L1
LD78-beta is a CC chemokine that is closely related to MIP-1 alpha. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. LD78-beta has been shown to exhibit potent activity in HIV suppression assays. Recombinant human LD78-beta is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CCL3L1
NCBI Gene ID
6349
UniProt
P16619
Accession Number
NP_066286.1
Accession Number mRNA
NM_021006.4
Chromosomal Location
17q21.1
Reactivity
Human
Cross Reactivity
Human
Sequence
APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract mouse BaF3 cells expressing the CCR5 receptor using a concentration range of 5-25 ng/ml.
Length
70
Form
Lyophilized
Molecular Weight
7.7 kDa
Host or Source
E. coli
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