I-TAC (CXCL11)
Human I-TAC (Interferon-inducible T cell alpha chemoacttractant) is an 8.3 kDa protein containing 73 amino acid residues. I-TAC is a novel non-ELR CXC chemokine. It is regulated by Interferon and has potent chemoattractant activity for IL-2 activated T cells, but not for freshly isolated unstimulated T cells, neutrophils, or monocytes.
Product Specifications
Synonyms
CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B
NCBI Gene ID
6373
UniProt
O14625
Accession Number
NP_005400.1
Accession Number mRNA
NM_005409.4
Chromosomal Location
4q21.2
Reactivity
Human
Cross Reactivity
Hamster, Mouse, Rabbit, Human, Monkey
Sequence
FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract IL-2 activated T-cells using a concentration range of 0.1-10.0 ng/ml.
Length
73
Form
Lyophilized
Molecular Weight
8.3 kDa
Host or Source
E. coli
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