Indian Hedgehog N-terminus
Indian Hedgehog (Ihh), Sonic Hedgehog (Shh), and Desert Hedgehog (Dhh) are important signaling molecules during embryonic development and are highly conserved within and across species. Mouse Ihh cDNA encodes a 411 amino acid (aa) polypeptide with a predicted 27 aa signal peptide. Post-translational processing yields a 19 kDa lipid-modified N-terminal domain that is the signaling molecule. At the cell surface, Ihh activity is mediated by binding the 12-pass transmembrane receptor, Patched (Ptc), and signaling through the 7-pass transmembrane G-protein coupled receptor, Smoothened (Smo) .
Product Specifications
Synonyms
IHH; BDA1; HHG2
NCBI Gene ID
16147
UniProt
P97812
Accession Number
NP_034674.1
Accession Number mRNA
NM_010544.2
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein of N-Terminal fragment of ihh protein
Clone
(#3A11)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
