IL-22
IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant murine IL-22 is a 3-34 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.
Product Specifications
Synonyms
IL22; IL-22; Iltif; IL-22a; ILTIFa
NCBI Gene ID
50929
UniProt
Q9JJY9
Accession Number
NP_058667.1
Accession Number mRNA
NM_016971
Chromosomal Location
10 D2; 10 67.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse IL-22
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Rabbit
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GNL3 (Guanine Nucleotide Binding Protein-like 3 (Nucleolar), C77032, E2IG3, MGC800, NS) (MaxLight 550)
GNL3 (Guanine Nucleotide Binding Protein-like 3 (Nucleolar), C77032, E2IG3, MGC800, NS) (MaxLight 550)
