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IL-21 receptor

IL-21 R, also called NILR (novel interleukin receptor) is a type I cytokine receptor with four conserved cysteine residues and an extracellular WSXWS motif. It is most closely related to IL-2 R beta and IL-9 R alpha. Mouse and human IL-21 R share 62% amino acid identity. IL-21 R is expressed on lymphoid tissues, peripheral B cells, and cell lines of T, B and natural killer cell lineage. IL-21 mediated signaling requires the common gamma chain in addition to IL-21 R.

Product Specifications

Synonyms

Il21r; NILR

NCBI Gene ID

60504

UniProt

Q9JHX3

Accession Number

NP_068687.1

Accession Number mRNA

NM_021887.2

Chromosomal Location

7; 7 F4

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Mouse recombinant EC domain of IL-21 R

Clone

(#7F27)

Applications

WB

Purification Method

Protein A/G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG1

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