IL-18 receptor alpha
Human IL-18 R cDNA encodes a 541 amino acid (aa) precursor type I membrane protein with a hydrophobic signal, an extracellular domain comprised of three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic region of approximately 200 aa residues. Human and mouse IL-18 R share 65% amino acid sequence homology. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta
Product Specifications
Synonyms
IL18RAP; ACPL; CD218b; IL18RB; CDw218b; IL-18 receptor
NCBI Gene ID
8807
UniProt
Q13478
Accession Number
NP_003846.1
Accession Number mRNA
NM_003855.3
Chromosomal Location
2q12
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-18 R beta EC domain
Clone
(#8H22)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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