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IL-18 receptor alpha

Human IL-18 R cDNA encodes a 541 amino acid (aa) precursor type I membrane protein with a hydrophobic signal, an extracellular domain comprised of three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic region of approximately 200 aa residues. Human and mouse IL-18 R share 65% amino acid sequence homology. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta

Product Specifications

Synonyms

IL18RAP; ACPL; CD218b; IL18RB; CDw218b; IL-18 receptor

NCBI Gene ID

8807

UniProt

Q13478

Accession Number

NP_003846.1

Accession Number mRNA

NM_003855.3

Chromosomal Location

2q12

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human IL-18 R beta EC domain

Clone

(#8H22)

Applications

WB

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

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