IL-15 receptor alpha
Interleukin 15 receptor alpha (IL-15 R alpha) is a high affinity receptor that specifically binds IL-15 and associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. IL-15 R alpha is expressed on a wide variety of Tand B cells as well as non-lymphoid cells. Human IL-15 R alpha shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
Product Specifications
Synonyms
Il15ra; AA690181
NCBI Gene ID
16169
UniProt
Q60819
Accession Number
NP_032384.1
Accession Number mRNA
NM_008358.2
Chromosomal Location
2 A1; 2 6.4 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse IL-15 alpha EC domain
Clone
(#7J23)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
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