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IL-15

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant murine IL-15 is a 13.3 kDa protein consisting of 115 amino acid residues.

Product Specifications

Synonyms

Il15; IL-15; AI503618

NCBI Gene ID

16168

UniProt

P48346

Accession Number

NP_032383.1

Accession Number mRNA

NM_008357

Chromosomal Location

8 C2; 8 38.0 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Recombinant mouse protein of IL-15

Clone

(#15B9)

Applications

WB

Purification Method

Protein A/G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG2

Frequently Asked Questions

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