IL-7R alpha
The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c) . Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.
Product Specifications
Synonyms
Il7r; CD127; IL-7Ralpha
NCBI Gene ID
16197
UniProt
P16872
Accession Number
NP_032398.3
Accession Number mRNA
NM_008372.4
Chromosomal Location
15 A1; 15 4.6 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein of IL-7alpha
Clone
(#6F11)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
Frequently Asked Questions
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