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IL-5

Interleukin 5 (IL-5) is a T cell-derived factor that promotes the proliferation, differentiation and activation of eosinophils. In mice, IL-5 is also a growth and differentiation factor for B cells. Various names previously used to describe IL-5 include: Tcell replacing factor (TRF), B cell growth factor II (BCGFII), B cell differentiation factor µ (BCDF µ), eosinophil differentiation factor (EDF) and eosinophil colony-stimulating factor (Eo-CSF) . Biologically active IL-5 is a disulfide-linked homodimer. Rat IL-5 is 94% and 70% identical to mouse and human IL-5, respectively.

Product Specifications

Synonyms

Il5; Il-5

NCBI Gene ID

16191

UniProt

P04401

Accession Number

NP_034688.1

Accession Number mRNA

NM_010558.1

Chromosomal Location

11 A5/B1; 11 29.2 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Recombinant mouse protein of IL-5

Clone

(#3M58)

Applications

FC, N

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG1

Frequently Asked Questions

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