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IL-5

Interleukin 5 (IL-5) is a T cell-derived factor that promotes the proliferation, differentiation and activation of eosinophils. In mice, IL-5 is also a growth and differentiation factor for B cells. Various names previously used to describe IL-5 include: Tcell replacing factor (TRF), B cell growth factor II (BCGFII), B cell differentiation factor µ (BCDF µ), eosinophil differentiation factor (EDF) and eosinophil colony-stimulating factor (Eo-CSF) . Biologically active IL-5 is a disulfide-linked homodimer. Rat IL-5 is 94% and 70% identical to mouse and human IL-5, respectively.

Product Specifications

Synonyms

IL5; EDF; TRF; IL-5

NCBI Gene ID

3567

UniProt

P05113

Accession Number

NP_000840.1

Accession Number mRNA

NM_000879

Chromosomal Location

5q31.1

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant IL-5

Clone

(#5F55)

Applications

WB, IHC (F)

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

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