IL-4

Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1) . IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.

Product Specifications

Synonyms

IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1

NCBI Gene ID

3565

UniProt

P05112

Accession Number

NP_000580

Accession Number mRNA

NM_000589

Chromosomal Location

5q31.1

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human IL-4

Clone

Rabbit IgG

Applications

ELISA, WB, N, IHC

Purification Method

Antigen-affinity purified

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Form

Lyophilized from PBS

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.