IL-4
Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1) . IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
Product Specifications
Synonyms
IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1
NCBI Gene ID
3565
UniProt
P05112
Accession Number
NP_000580
Accession Number mRNA
NM_000589
Chromosomal Location
5q31.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-4
Applications
ELISA, WB
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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