IL-2 receptor alpha
IL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas. Interleukin-2R Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (22-213) corresponding to the mature IL2-R protein with an amino terminal hexahistidine tag. The IL-2R is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
IL2RA; CD25; IL2R; TCGFR; IDDM10
NCBI Gene ID
3559
UniProt
P01589
Accession Number
NP_000408.1
Accession Number mRNA
NM_000417.2
Chromosomal Location
10p15-p14
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-2 R alpha EC domain
Clone
(#1X27)
Applications
WB, IHC (P), N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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