IL-2 receptor alpha

IL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas. Interleukin-2R Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (22-213) corresponding to the mature IL2-R protein with an amino terminal hexahistidine tag. The IL-2R is purified by proprietary chromatographic techniques.

Product Specifications

Synonyms

IL2RA; CD25; IL2R; TCGFR; IDDM10

NCBI Gene ID

3559

UniProt

P01589

Accession Number

NP_000408.1

Accession Number mRNA

NM_000417.2

Chromosomal Location

10p15-p14

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human IL-2 R alpha EC domain

Clone

(#1X27)

Applications

WB, IHC (P), N

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.