IL-2
Interleukin 2 (IL-2) was initially identified as a T cell growth factor that is produced by T cells following activation by mitogens or antigens. Since then, it has also been shown to stimulate the growth and differentiation of B cells, natural killer (NK) cells, lymphocyte activated killer (LAK) cells, monocytes/macrophages and oligodendrocytes. At the amino acid sequence level, there is approximately 60% - 90% similarity between species. Mature human IL-2 shows 65%, 67%, 72%, 78%, and 64% aa identity to mouse, rat, pig, cat, and cow IL-2, respectively.
Product Specifications
Synonyms
IL2; IL-2; TCGF; lymphokine
NCBI Gene ID
3558
UniProt
P60568
Accession Number
NP_000577
Accession Number mRNA
NM_000586
Chromosomal Location
4q26-q27
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-2
Applications
ELISA
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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