Rat Anti-Mouse IL-1 receptor antagonist Monoclonal Antibody
IL-1 receptor antagonist (IL-1ra) was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The protein shows 26% amino acid homology to IL-1 beta and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells. In mouse, IL-1RII does not bind IL-1ra.
Product Specifications
CAS Number
9007-83-4
Synonyms
Il1rn; IL-1ra; F630041P17Rik
NCBI Gene ID
16181
UniProt
P25085
Accession Number
NP_112444.1
Accession Number mRNA
NM_031167.5
Gene Location
2 A3; 2 10.0 cM
Host
Rat
Origin Species
Mouse
Species Reactivity
Mouse
Target Antigen
Recombinant Mouse protein of IL-1R antagonist
Isotype
IgG2
Clone
(#5K21)
Validated Applications
WB
Purification Method
Protein G/A chromatography
Form
Lyophilized
Buffer
PBS
Reconstitution
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Shipping Conditions
Room Temperature
Storage Conditions
Frequently Asked Questions
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