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IL-1 R8

The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig) -like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. Interleukin 1 receptor accessory protein-like 1 (IL-1 RAPL1), also known as IL-1 R8, Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL-1 receptor-related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily.

Product Specifications

Synonyms

IL1RAPL1; IL1R8; MRX10; MRX21; MRX34; OPHN4; IL1RAPL; TIGIRR-2; Interleukin 1 receptor 8

NCBI Gene ID

11141

UniProt

Q9NZN1

Accession Number

NP_055086.1

Accession Number mRNA

NM_014271.3

Chromosomal Location

Xp22.1-p21.3

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human IL1-R 8 EC domain

Clone

(#3R16)

Applications

WB

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG2

Frequently Asked Questions

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