IL-1 R8
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig) -like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. Interleukin 1 receptor accessory protein-like 1 (IL-1 RAPL1), also known as IL-1 R8, Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL-1 receptor-related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily.
Product Specifications
Synonyms
IL1RAPL1; IL1R8; MRX10; MRX21; MRX34; OPHN4; IL1RAPL; TIGIRR-2; Interleukin 1 receptor 8
NCBI Gene ID
11141
UniProt
Q9NZN1
Accession Number
NP_055086.1
Accession Number mRNA
NM_014271.3
Chromosomal Location
Xp22.1-p21.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL1-R 8 EC domain
Clone
(#3R16)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG2
Frequently Asked Questions
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