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IL-1 R6

The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig) -like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. IL-1 Rrp2, also known as IL-1 R6, is a transmembrane protein belonging to the IL-1 receptor family. It is a ligand binding subunit that associates with IL-1 RAcP to form a functional receptor complex for IL-1F6, IL-1F8, and IL-1F9.

Product Specifications

Synonyms

Interleukin-1 Receptor 6

NCBI Gene ID

8808

UniProt

Q9HB29

Accession Number

NP_003845.2

Accession Number mRNA

NM_003854.2

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human IL1-R 6 EC domain

Clone

(#5T37)

Applications

WB

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

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