IGF-2

Insulin-like growth factor (IGF) -I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity.

Product Specifications

Synonyms

IGF2; IGF-II; PP9974; C11orf43

NCBI Gene ID

3481

UniProt

P01344

Accession Number

NP_000603.1

Accession Number mRNA

NM_000612.4

Chromosomal Location

11p15.5

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human IGF-II

Clone

(#5L20)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.