IFN-lambda-1 (Animal Free)
IFN lambda-1, -2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and the interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14) . Signaling through this receptor system induces antiviral defenses similar to, but distinct from, that of type I interferons. Recombinant Human IFN-λ1 is a 19.8 kDa protein containing 178 amino acid residues.
Product Specifications
Synonyms
IL29; IFNL1; IL-29; IL-29, IL-28A; IL-28B
NCBI Gene ID
282618
UniProt
Q8IU54
Accession Number
NP_742152.1
Accession Number mRNA
NM_172140.1
Chromosomal Location
19q13.13
Reactivity
Human
Cross Reactivity
Human, Monkey
Sequence
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Length
178
Form
Lyophilized
Molecular Weight
19.8 kDa
Host or Source
E. coli
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