IFN beta (Animal Free)
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues.
Product Specifications
Synonyms
IFNB1; IFB; IFF; IFNB
NCBI Gene ID
3456
UniProt
P01574
Accession Number
NP_002167.1
Accession Number mRNA
NM_002176
Chromosomal Location
9p21
Reactivity
Human
Cross Reactivity
Human, Mouse
Sequence
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Length
166
Form
Lyophilized
Molecular Weight
20 kDa
Host or Source
E. coli
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