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ICAM-1 (CD54)

Intercellular adhesion molecule 1 (ICAM-1), also known as CD54, binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface.

Product Specifications

Synonyms

Icam1; CD54; Ly-47; Icam-1; MALA-2

NCBI Gene ID

15894

UniProt

P13597

Accession Number

NP_034623.1

Accession Number mRNA

NM_010493.2

Chromosomal Location

9 A3; 9 7.0 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Cytokine stimulated Mouse Endothelial cells

Clone

(#MAB0802)

Applications

IHC (P), FC

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS (sterile)

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG2

Frequently Asked Questions

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