ICAM-1 (CD54)
Intercellular adhesion molecule 1 (ICAM-1), also known as CD54, binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface.
Product Specifications
Synonyms
Icam1; CD54; Ly-47; Icam-1; MALA-2
NCBI Gene ID
15894
UniProt
P13597
Accession Number
NP_034623.1
Accession Number mRNA
NM_010493.2
Chromosomal Location
9 A3; 9 7.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Cytokine stimulated Mouse Endothelial cells
Clone
(#MAB0802)
Applications
IHC (P), FC
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS (sterile)
Storage Conditions
Host or Source
Rat
Isotype
IgG2
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